IN VITRO FERTILIZATION (IVF)

What is IVF?
IVF stands for in vitro fertilization, and it refers to a process in which egg cells are harvested from the prospective mother and sperm cells from the prospective father, with the eggs fertilized in a laboratory setting, and then implanted into the uterus of the prospective mother.
IVF treatment was first applied in 1978. While it was originally intended to be used only for women with blocked or damaged fallopian tubes during this time period, it has evolved into a method that now solves 80 percent of infertility problems, including many cases of male infertility.
This method, which is the most successful among assisted reproductive methods, can be used when a couple is unable to conceive despite having regular and unprotected sexual intercourse for a year. If the prospective mother is 35 or older, she should wait six months for a natural pregnancy before consulting a specialist.

What Happens During the IVF Procedure?

This method has 6 basic steps. These are;

1. The goal of ovarian stimulation is to harvest as many mature eggs as possible. This necessitates a number of medications for the prospective mother. This phase begins on the third day of the menstrual cycle and lasts for the next twelve days. At this point in the process, the prospective mother is required to make frequent trips to the center. This will allow for better management of drug response and egg development.

2. The stimulated eggs are retrieved with a small procedure. Sedatives or local anesthesia may be used to keep the prospective mother comfortable during the procedure; however, some women report experiencing cramping the day after the procedure. At the stage when the eggs are harvested, the father-to-be also provides a sperm sample. Sperm cells can be taken from potential fathers with azoospermia (no sperm) using the Micro TESE method.

3. The sperms obtained from the man's ejaculate are prepared for fertilization of the eggs.

4. In the laboratory, sperm and eggs are placed in incubators for fertilization, and the incubators ensure fertilization occurs. It is possible to directly implant a single sperm into an egg in less fertile conditions. The eggs are kept under observation to ensure that fertilization has taken place. When cell division begins, these eggs are now referred to as embryos.

5. Fertilized eggs that have been stored in the laboratory for two to three days are inserted into the uterus using a painless procedure. The eggs are transferred after being kept in the laboratory following fertilization. This process takes 5-10 minutes. Sexual activity is not advised until the pregnancy test has been carried out. Paracetamol group drugs can be used for pain relief. One day after the transfer, you can take a warm shower.

6. Pregnancy test; A pregnancy test is performed 12 days after the transfer process to determine the state of pregnancy. The test is the same as any other pregnancy test performed in every hospital.

What Factors Will Affect IVF Treatment?

1. Absence of eggs in the prospective mother

2. Lack of fertilization

3. Problems during the transfer

4. Azoospermia

5. Bleeding before pregnancy test

6. Overstimulation of ovaries

Is Miscarriage Risk High After IVF Treatment?

Miscarriage rates in IVF treatment have similar values to normal pregnancy if the necessary medical support is applied in the first three months of pregnancy.

What Are The Factors That Have A Negative Impact On IVF Success?

The success rate of IVF depends on a variety of factors. The character of the patient and their approach to treatment are two of them. Other factors that have a negative impact on the success of IVF include:

1. Woman's Age

2. Ovarian Reserve

3. Structure of Cells Obtained in Women and Men

4. Intrauterine Membrane Issues in Women

How Long Does IVF Therapy Take?

It takes about 15 days, excluding the examinations prior to the start of IVF treatment and the doctor's evaluation of the couples. Because male patients' only role in the treatment is to provide sperm, the treatment only takes 10 minutes for them. Procedures applied to women are completed within 10 days. However, women are not constantly treated during this process. During this time, the woman is kept under observation. The start of treatment begins by using hormones to stimulate the ovaries to produce multiple eggs. The obtained eggs are collected, fertilized with male sperm, and an embryo is formed. With the completion of the embryo transfer, IVF treatment is completed in a total of 15 days.
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